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What is Provigil?

Provigil is a brand name for Modafinil nootropic medicine. Manufactured by Teva Pharmaceuticals USA, Inc., this medicine falls under the class of drugs called eugeroic also known as wakefulness enhancers or wakefulness promoting agents. This medicine helps in treating narcolepsy, excessive daytime sleepiness, shift work sleep disorder, and daytime sleepiness associated with sleep issues. Other drugs belonging to this category are Armodafinil and Adrafinil. Armodafinil works as a weak, atypical, selective dopamine reuptake inhibitors.

Chemical structure of Provigil 200mg tablets

How to choose the right Provigil dosage?

Provigil 200mg tablet is the standard dosage that can be used to treat excessive daytime sleepiness. However, your doctor can make changes in the dosage pattern. People dealing with CFS or ME can take Provigil 200mg to ease symptoms. Dosages can be increased up to 400mg depending on the response given by the patient. Patients with severe hepatic or renal issues need to consume the drug under medical supervision. Generally, the dosage for these people ranges from 100 to 200mg.

How long does Provigil take to work?

The smart pill takes 45 minutes to an hour to start working. It needs to be taken almost an hour before you start working to get the optimal results. When taken an empty stomach, the time of action reduces giving you faster results. If taken along with food, results may get delayed. Half-life of Provigil is pretty high (12 to 14 hours) and thus one dosage is enough to keep you going all day long.


How long does Provigil pills stay in the system?

The medication stays in your system for about 82 and half hours. Factors such as dosage strength, individual physiology and time span play an important role in keeping the drug in your system. To get more information about the same, you need to talk to your doctor.

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What causes sleep issues?

Sleep issues occur due to various reasons. Regardless of the causes, the final outcome of any slumber issue is the disrupted body’s natural sleep cycle or circadian rhythm and excessive daytime sleepiness or less attentiveness.


Factors responsible for the onset of slumber issues:

  • Physical conditions
  • Medical issues such as asthma
  • Psychological conditions like depression
  • Alcohol abuse
  • Genetic reasons
  • Night shift work culture
  • Medicines
  • Ageing

How losing sleep affects body?

Serious health problems: Much to your surprise, majority of the health issues you are prone to develop occur due to heavy loss of slumber. As per the estimated calculation of a group of studies, around 90% people suffering from insomnia have reported some sort of health issues with the onset of sleep issue.


Sleep disorders or sleep loss can put you at risk of developing following health issues:

  • Heart disorders
  • Heart attack
  • Irregular heartbeat
  • Heart failure
  • Hypertension
  • Stroke
  • Diabetes


Low libido: Sleep specialists have mentioned that men and women who are sleep deprived have reported low libido issue. Sleep loss results ion low level of energy along with elevated stress levels and drowsiness are some the reasons for reduced sex drive. As per a study published in the Journal of Clinical Endocrinology & Metabolism in 2002, men with sleep apnea often show low levels of testosterone. Studies have also shown that men suffering from severe sleep apnea showed abnormally reduced amount of testosterone hormone.


Impaired thinking and learning process: Sleep has a deep connection with better cognitive health. When you lose on slumber, it starts interfering with your attentiveness, concentration power, problem solving and reasons process. This, altogether, makes it difficult for you to learn things. Sleep cycles play a huge role in blending memories. But if you are sleep deprived, it becomes difficult for consolidating learned experiences into memories because your learning ability has been hampered.


Ages the skin:Pale skin and puffy eyes are common signs of not getting enough sleep but if you are losing slumber on a daily basis, you could show signs such as fine lines, under eye dark circles, and tired skin. This happens because of increased level of stress hormone cortisol. When found in excess amount, this hormone breaks down the skin collagen.


Weight gain / Difficulty losing weight When you lose on snooze, you tend to put on weight or it makes you difficult to shed those extra pounds. As per a study done in 2004, people who got less than six hours of sleep have increased tier risk of being obese by approximately 30% than those who got snooze. Recent study has shown that sleep loss is related to production of peptides which regulate appetite. Sleep deprived people show cravings for junk foods which are high in fats and sugar.


Hampered longevity: British researchers observed how sleep patterns and changes in them altered the mortality of over 10,000 British civil servants for more than 20 years. The results showed that those who had less than five hours of sleep have doubled the risk of developing cardiovascular issues and death risk from those issues increased. The study is called as “Whitehall II Study”.


Depression: Lack of sleep and sleep issues have been linked with depression symptoms. Insomnia, the most common slumber disorder, has shown a strong connection with depression. In fact, insomnia occurs as one of the major symptoms of depression. In a study performed in 2007 with 10,000 participants, those suffering from insomnia were at higher risk of getting depression than those without insomnia.


Forgetfulness: American and French researchers estimated that consolidation of memory happens in events called “sharp wave ripples” which occur in the brain. These ripples are responsible for conveying learned information from the hippocampus to the neocortex of the brain. This part of the brain stores long-term memory. Sharp ripple waves normally occur during deepest levels of slumber.

How Provigil works for sleep issues?

The exact mechanism of action of Provigil is not known fully yet. However, various studies and researches have backed up this statement that the medicine interferes with the secretion and re-uptake process of certain brain chemicals or neurotransmitters.


Provigil 200mg is fortified with Modafinil which is an active chemical. It enhances production of specific stimulatory neurotransmitters such as glutamate, acetylcholine along with certain mixed neurotransmitters like serotonin, norepinephrine and histamine. However, the major target is the dopamine receptor. By stopping the re-uptake process of dopamine, the medicine increases concentration of dopamine within the brain which causes mood lift and enhanced motivation. Buy Provigil Online.


To bring wakefulness and to boost focus, the medicine increases the concentration of norepinephrine or noradrenaline. Provigil 200mg also affects GABA neurotransmitter which is essential for sleep regulation. By reducing histamine levels in the brain, the drug helps in keeping one awake for longer period of time.


Provigil anxiety is a thing and it can be explained on the basis of the drug’s ability to increase secretion of norepinephrine. A high level of this neurotransmitter is related to anxiety. This happens when you combine Provigil and caffeine and with other stimulators.

Is Provigil a stimulant?

Provigil has Modafinil as its active chemical content. It is a stimulant but it is way better than the conventional ones. Contrasting to amphetamines, Modafinil has said to shown minimal side effects to the prescribed therapeutic dosage. Furthermore, it does not interfere with the normal sleep cycle and also shows low abuse potential. It means, it is not habit forming or the risk is low. Provigil tablet has shown alertness enhancing properties in sleep-deprived or sleep issues affected subjects.

Provigil vs. Nuvigil: What is the difference?

Provigil has Modafinil and Nuvigil has Armodafinil as its core content respectively. Chemically, Modafinil is a mixture of R- and S-enantiomers and Armodafinil is the R-enantiomer. The R-enantiomer is the long-acting isomer of Modafinil which explains similar half-life of both the molecules which is 15 hours. Armodafinil shows a slightly shorter time to peak which is 2 hours as compared to Modafinil which has a peak time of 2 to 4 hours. Further, the former shows a fewer side effects in comparison of the latter drug. Nonetheless, there is no clinical data to prove that Nuvigil is superior to Provigil.

How to Buy Provigil Online

First and foremost, you need to get your sleep disorder diagnosed by a doctor. An accurate diagnosis is required for getting right kind of medicine. Once the diagnosis is done and Provigil 200mg tablets are prescribed to you, you can visit our website to buy the study pills. However, the good news is that you can get Provigil without prescriptions as well. Buy Provigil Online.

What are the precautions I need to follow?


For Provigil 200mg to deliver the best results, you must learn and implement precautionary measures stated by your health care provider. Following these rules will help you get safer outcome with the drug and it also ensures fewer side effects.


  • Do not exceed the dosage than the prescribed amount.
  • Always read the patient information leaflet that comes with the box.
  • It is better to take the drug for prescribed period of time.
  • Take the drug with an empty stomach to speed up the absorption process.
  • Do not consume more than the prescribed amount until being told.


How long does Provigil take to show results?

It takes around 45 to 60 minutes to start working. You need to take the pill with a large glass of water preferably on an empty stomach to speed up the process of drug absorption.


How long do Provigil effects last?

The half-life of the medicine is 12 to 14 hours which means one pill of Provigil 200mg is enough to keep you alert and awake throughout the day.


How should I store the drug?

Store the drug in a clean and cool place. Do not refrigerate it. Keep the bottle away from direct sunlight and moisture.


Can I break or crush Provigil 200mg pills?

You must swallow the pills as a whole. Breaking or crushing the pill might alter the amount of drug being consumed by you and ultimately it changes the final outcome.


Side effects and warnings


Every medicine that you consume is a mass of chemicals and it is possible to get some unpleasant, unwanted effects along with the desired ones. These unpleasant effects are termed as side effects. In case of Provigil 200mg pills, many people get along with the drug whole some show onset of side effects. They could be mild to severe in form depending on mode of consumption, strength or dosage etc. You need to speak with your doctor to get more information.


List of known side effects of Provigil


  • Upper respiratory tract infection
  • Dizziness
  • Headache
  • Nausea
  • Agitation
  • Anxiety
  • Nervousness
  • Insomnia or trouble sleeping
  • Dry mouth

Get immediate medical help if following side effects occur:

  • Fever
  • Hallucinations
  • Chest pain
  • Depression
  • Faster or irregular heartbeat
  • Mental or mood changes


For detailed information, you can read the patient information leaflet provided along with the medicine or speak to your doctor.

Drug interaction


It is very much possible that the drugs you are taking already interfere with the working of Provigil dosages that you are being put on. Certain drugs affect the way this smart drug works while in some cases, this smart drug can reduce the efficacy of other drugs. In both the cases, you suffer from a bunch of uneasy symptoms or side effects. It is possible to prevent drug interaction to get better Provigil experiences.


Drugs that interact with Provigil 200mg pills and vice versa:

  • Oral birth control pills
  • Antidepressants
  • Anti-fungal medicines


Provigil affects the effectiveness of oral birth control pills and thus one needs to look for alternative birth control methods. Consuming the drug with alcohol is never a good idea.


Pregnancy and breastfeeding

Provigil might affect the growing fetus and thus it is not recommended for pregnant women. The active content Modafinil might pass into the breast milk however there is no clinical data to support this statement. Therefore, breastfeeding women must use the drug only when it is absolutely needed and recommended by a doctor.


Driving and operating machinery

Though Provigil online is known for its wakefulness promoting properties, it tends to induce dizziness in its users and thus it is not recommended to drive a car or operate heavy machinery post consumption of the drug.


Allergic reactions

It is possible to develop allergic reactions to the chemically active core of Provigil. If you start developing allergic symptoms after consuming the drug, it is better to get medical help and stop using the drug completely. If you have shown allergic reactions to the drugs similar to smart drugs, you need to consult with the doctor before buying Provigil online.


Questions and Answers

What are the alternatives to Provigil?

Provigil is a brand name for Modafinil. You can find various generic as well as branded alternatives for Provigil 200mg pills. There are Modvigil, Adrafinil, etc. You can go for [other nootropic medicines which deliver the similar results. There is Phenylpiracetam, Pramiracetam, Sulbutiamine etc., which can be used after a proper medical consultation.


Can elderly and teenagers buy Provigil online?

Though Provigil 200mg pills have been useful in adults, it is not meant for elderly people. This medicine increases risk of severe side effects in oldies and that is why it is not recommended for them. Teenagers cannot buy Provigil online for the same reason. Adults with health issues such as cardiovascular issues, liver or kidney ailments need to speak with their doctors.


Can I consume Provigil 200mg pills with other medicines?

It is not recommended to mix up your medicines with this smart drug. You need to ask your doctor and keep sufficient time gap between the administration of smart drugs and other drugs you are taking currently. Other medicines include herbal and natural supplements as well.


How can I buy Provigil online safely?

It is important to study the website you are planning to buy Provigil 200mg pills from. Read all the information about the website provided and also check for the documentation they have listed. Get your queries solved by the customer care team.

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